Andrew L. Stoll See book keywords and concepts | The Antioxidant Boost
Hope of developing a natural treatment for schizophrenia is strengthened by recent evidence that vitamins c and E might boost the EPA effect. In research out of the Medical College of Georgia in Augusta, psychiatric researcher Dr. Sahebarao P. Ma-hadik has found that patients with schizophrenia contain very high blood levels of biochemical markers of what lipid scientists call lipid peroxidation—the oxidation, or chemical destruction, of fatty acids by oxygen and other highly reactive chemicals, such as free radicals, in the body. | J. Robert Hatherill See book keywords and concepts | Effect of wheat fiber and vitamins c and E on rectal polyps in patients with familial adenomatous polyposis. / Natl Cancer Inst (1989) 81(17):1290-97.
Goodinan, M. T. Dietary factors in lung cancer prognosis. Eur J Cancer (1992) 28(2/3):495-501.
Howe, G. R. Dietary intake of fiber and decreased risk of cancers of the colon and rectum: evidence from the combined analysis of 13 case-control studies J Natl Cancer Inst (1992) 84(24):1887-96.
Willett, W. C. Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. New Engl J Med (1990) 323:1664-72. | John R. Smythies See book keywords and concepts | Lipoic acid regenerates the active forms of vitamins c and E. It is found in dark green leafy vegetables.
Small-molecule, fat-soluble antioxidants have to be obtained from plants because animals, including humans, cannot make them. In the case of this class of antioxidants, there are significant chemical differences between the natural forms found in plants and the forms synthesized by chemists. The natural form consists of one stereoisomer, the synthetic variety of eight. | If the focus of study is, for example, the antioxidants vitamins c and E and beta-carotene, researchers then estimate how much of these vitamins the reported diet would contain. They partition the sample into several groups, taking data from those with the highest level of intake (usually the upper fifth) and those with the lowest (usually the lowest fifth). Researchers then ascertain the number of cases of the particular disease under study that have occurred in each group at the two extremes, the highest fifth and the lowest fifth. | This means that the blood levels of these antioxidants, especially of vitamins c and E and beta-carotene, will tend to fall as long as the degree of oxidative stress is greater than the capacity of the body to mobilize enough antioxidant defenses to deal with the situation. The blood levels of these antioxidants can be measured, thus indicating how the battle is going.
3. Antioxidant enzymes are synthesized when they are needed. For example, under oxidative stress, levels of SOD, CAT, and GSHpx tend to rise in the blood and body tissues. | They gave the ANICA protocol—a mixture of antioxidants and minerals (including beta-carotene, vitamins c and E, selenium, gamma-linoleic acid, and 90 mg of vitamin Q10)—and found that no patients died (the expected number was four); none showed further metastases or weight loss; the need for painkillers was reduced; and six patients showed apparent remission. The authors recommend 300 mg per day of vitamin Q10 to attain a blood level of 20 Lig/ml. The wide mixture of antioxidants may be a key to their apparent success.
However, other investigations have yielded conflicting or negative results. | Barnet Meltzer, M.D. See book keywords and concepts | Cabbages also contain a plentiful supply of vitamins c and E, calcium, iron, potassium, and fiber.
Selection and Care: Select fresh, firm, crisp cabbages with compact heads, heavy for their size, and tightly wrapped leaves free of discoloration at the edges.
Optimal Use and Combining: Raw green and red cabbage can be tossed in salads or grated for a vegan coleslaw. Cabbage soup is particularly fortifying in cold winter months. Cabbage, cauliflower, and the rest of the cruciferous family mix well with beets, carrots, and other root vegetables. | Nutrient Value: In addition to bromelain, pineapples contain significant amounts of vitamins c and Bj.
Selection and Care: Fragrance is the key to determining freshness: A sweet aroma indicates that the fruit is mature. Look for bright green tops, securely attached crowns, and choose the deepest yellow-orange pineapples. Try to pull out one of the spines—if the pineapple is ripe, it will come out easily. The fruit should feel dry and heavy for its size, and should be free of dark, decayed spots.
Optimal Use and Combining: Serve pineapple fresh with other citrus fruits. | Francisco, M.D. Contreras See book keywords and concepts | Among other nutrients, the most outstanding antioxidants are the vitamins c, E and beta-carotene. Selenium is an antioxidant mineral essential to any program of cancer preventive care. Make sure it is part of your arsenal, and is combined with all the other minerals. Other potent free-radical fighting supplements are coenzyme Q10, SOD (superoxide dismutase), and vitamin B17, otherwise known as Laetrile and Amygdalin.
In theory, if we are able to neutralize free radicals, we can diminish the incidence of disease and slow the aging process. Dr. John P. Richey, Jr. | Research biochemists know it is more than just beta carotene and vitamins c and E in vegetables and fruits that help prevent cancer. Folic acid, one of the B vitamins, is a powerful nutrient, and often deficient in those who need it the most.
Researcher Edward Giovannucci, Harvard Medical School, thinks folic acid may help turn off cancer genes. Giovannucci's team discovered that a high intake of folic acid, from fresh vegetables and fruit and vitamin supplements, lowered the risk of tumor development.
Other research shows folic acid directs the growth of new cells in the body. | Gale Maleskey See book keywords and concepts | Like vitamins c and E, selenium helps to prevent damage throughout the body from free-roaming, unstable molecules called free radicals. "Selenium's role in the body is complex, however, and not yet fully understood," says Orville Levander, Ph.D., a research leader at the U.S. Department of Agriculture Beltsville Human Nutrition Research Center in Maryland. "There are probably a dozen or so different selenium-containing proteins in the body," he says. "Some have antioxidant activity, and some apparently have other roles. | Early studies show that it is prudent to add vitamins c and E to your sunscreen to protect against ultraviolet phototoxic injury to your skin," he says. Sunscreens with these vitamins already added can be found in drugstores.
You can also prepare your skin to withstand the harmful effects of ultraviolet rays by taking a beta-carotene supplement, says Dr. Hecht. He recommends taking 100,000 IU of beta-carotene for a month or two before you plan to expose yourself to intense sunlight—before the first beach day, for instance, or before a midwinter skiing vacation. | Antioxidants Keep Things Clear
Most of the evidence for supplements' effect on cataracts points to vitamins c and E and selenium.
The lens of the eye has the second highest concentration of vitamin C of any organ in the body, says Mark Lamden, N.D., a naturopathic doctor and adjunct faculty member at Bastyr University in Bothell, Washington. Any vitamin C that you get—from food or supplements—can help your lenses in a big way.
There's another reason to take vitamin C, however. It's an antioxidant, and you need its power because the eyes are prime sites of what are called oxidative processes. | J. Robert Hatherill See book keywords and concepts | Green tea can protect from tobacco smoke toxicity, and cabbage is high in vitamins c and E.
Tobacco smoke is a complex mixture containing over 4,000 identified components. When tobacco burns it causes unstable, highly reactive compounds called free radicals to form. Free radicals are molecules that have an imbalance in their electrons that compels them to be reactionary, so they race wildly around in your cells searching for more electrons. | Earl Mindell See book keywords and concepts | Meticorten,
Prednisolone™, Orasone™)
Propantheline (Pro-Banthine™)
Beta-carotene, vitamin B12, sodium, potassium
B6
Vitamins K&B12
Vitamins A, D, E, K, calcium & phosphorus
Vitamins B6, C, zinc, & potassium
Folic acid
Folic acid
Vitamins Bl, C & folic acid
Folic acid, vitamins c, B2, B6,B12,&E
Vitamin B6
Vitamins B6, niacin, & K Folic acid
Vitamin B12, D, folic acid, & calcium
Vitamins B6, D, C, zinc, & potassium
Vitamin K
Proton pump inhibitors (e.g., Prevacid™, Prilosec™)
Pyrimethamine (Daraprim™)
Sulfonamides, systemic (e.g. | Gary Null See book keywords and concepts | There may also be too little calcium and too much phosphorus in their diets, which in combination with a lack of adequate vitamins c and D, could create this condition involving a depressed rate of bone mineralization. Sedentary living also contributes to osteoporosis.
Doctors now know that if their female patients start a regimen of calcium and vitamin D supplements at the age of thirty, there is a far slimmer chance of their developing osteoporosis. An adequate diet in every respect and sufficient exercise can also greatly decrease the risk of developing this disease. | If you want to guard against the dangers of iron deposits, make sure your diet includes plenty of the B vitamins, vitamins c and E, and protein.68 Taking adequate amounts of E is also a good preventative against the deposits' causing cancer.69
Studies conducted on 37 volunteers resulted in the conclusion that the consumption of tea and coffee, especially in conjunction with a meal, tends to inhibit iron absorption. It was interesting to note that coffee consumed one hour before a meal was not as effective in preventing iron absorption as when taken with the meal. | And finally, there is some evidence that bioflavonoids with vitamins c and E may even offer relief from hot flashes associated with menopause.
Remember, the bioflavonoids are water soluble; what your body doesn't need is excreted through the skin and urine. If you suffer from a condition in which they might be beneficial, there can be no harm in giving them a try.
VITAMIN P FOR DEPRESSION
One orthomolecular physician, in measuring the brain waves of volunteers who had taken rutin in 50 milligram doses, concluded that the bioflavonoid is a sedative. | In numerous experiments and clinical practice, mental illness or emotional imbalance has been effectively treated with megadoses of vitamins c, E, B3, and B6.
In light of these discoveries, one sad irony in the current conventional approach to mental illness is that the very chemicals that are used to treat the symptoms of mental disorders may alter the way in which the body uses nutrients, thus altering the patient's nutritional status and perhaps sharpening the biochemical imbalance that is at the heart of the disorder.
Can vitamins really help the victims of mental illness? | If you are deficient in vitamins c and E and/or nicotinic acid, you are at special risk. For example, when the body's cells are saturated with ascorbic acid, cholesterol levels tend to decline. Also, sufficient vitamin E can help prevent heart disease by improving blood circulation and blood oxygen efficiency. Nicotinic acid, also known as B3, is the third nutrient commonly missing in the American diet, which so often is implicated in the development of heart disease. These findings have been noted in Supernutrition by Dr. Richard Passwater.
5. What about mineral deficiency? | It is also the mineral activator of vitamins c and E.12 In fact, its work throughout your body is so comprehensive that it is easy to understand why it is found in greater quantities within your cells than any other mineral except potassium.13
Magnesium also maintains working relationships with some of the hormones in your body: aldosterone, the other adrenal hormones, your sex hormones, cortisone, and parathormone. Aldosterone, which cannot be synthesized without magnesium, is vital in maintaining a balance of minerals within your body. | Muhammed Majeed, Ph.D. Vladimir Badmaev, M.D., Ph.D. Uma Shivakumar, Ph.D. R. Rajendran, M.S. See book keywords and concepts | This damaging reaction can be blocked by certain substances in food, including natural phenolics such as curcuminoids, vitamins c and E, and beta-carotenes.
Both turmeric extract and curcumin inhibited the nitrosation of methyl urea with sodium nitrite at acidic pH.98 Turmeric extract and curcumin block the nitrosation reaction of fish extract with sodium nitrite. The nitrosation inhibition by curcumin is mediated through its scavenging, or neutralizing, capability of nitrite ions from the media. | The Life Extension Editorial Staff See book keywords and concepts | C and A do not. Vitamin C inhibits the growth of tumot cells but does not cause differentiation (Cameron et al. 1979; Prasad et al. 1979). These studies show that antioxidants do not produce similar effects on different types of cancer cells.
Depending on the type of therapy used, antioxidants may affect cancer cells in many different ways. | Dr. Mary Dan Eades See book keywords and concepts | Some research suggests combining vitamins c and E works best at reducing the risk of cancerous change of colon polyps. Recommendation: Take 400 mg of each vitamin daily. Increase the vitamin E in small increments as suggested above to be sure your blood pressure does not increase on a larger dose.
• Vitamins A, C, and E have also been studied in combination in people who have had colon polyps removed and are more likely to develop more polyps, and are therefore at a higher risk for colon cancer. | Recommendation: Take 50 mg riboflavin along with the doses of vitamins c and E and selenium suggested in this section.
• Deficiency of zinc, necessary for normal glucose use by the cells of the lens, seems to promote the formation of cataracts in laboratory animals (including fish) and in people. Supplementation with zinc becomes especially important for the elderly, who frequently suffer from this mineral deficiency and more often develop cataracts. Recommendation: Take 50 mg to 100 mg of chelated zinc (zinc aspartate or zinc picolinate) daily for 6 to 8 weeks. | Earl Mindell and Hester Mundis See book keywords and concepts | MY SUGGESTION If you do indulge in bacon, be sure you're ingesting enough vitamins c, A, D, and E to help counteract the nitrites. (For the best natural sources, see section 145.) I'd also recommend the following daily supplement regimen:
?An all-natural, high-potency multiple vitamin and amino acid?chelated mineral complex (containing no preservatives or artificial colors), preferably one with digestive enzymes for better absorption
? | Donald R. Yance, j r.,C.N., M.H., A.H.G., with Arlene Valentine See book keywords and concepts | It contains high-quality protein (58 percent protein), vitamins (all the B vitamins plus vitamins c and E), minerals, including many important trace minerals, omega-3 fatty acids, and mucopolysaccharides. Chlorella has been shown to improve immune function in people undergoing chemotherapy and/or radiation therapy. Chlorella increases macrophage activity, activates both T-cells and B-cells, and has shown antitumor effects. In addition, chlorellan, a substance found in chlorella, stimulates interferon production. | Dr. Mary Dan Eades See book keywords and concepts | If you eat a diet in which the majority of your fat and oil consumption comes from these polyunsaturated sources, it increases your body's need for antioxidant protection, such as you would get from vitamins c and E. Without this protection, a high intake of polyunsaturated fats and oils can damage your tissues and your immune function, and thereby increase your risk for breast cancer.
Also, to keep these chemically unstable oils on the consumer shelf longer without "going bad," food manufacturers usually heat them to high temperatures. | Michael Lerner See book keywords and concepts | Take a few vitamin supplements—a multivitamin and perhaps some additional antioxidant vitamins c, E, and A—to ensure that your nutritional needs are met, especially as you go through hospitalization and treatment, which may cause nutrient deficiencies.
"As far as alternative nutritional therapies go, I have not studied them carefully but I would have to say to you that the evidence is mixed. Some patients apparently do well on those therapies, at least in terms of how they feel, but others do not. | Earl Mindell See book keywords and concepts | CAUTION: Large doses of cysteine/cystine, vitamins c and Bl are not recommended for anyone with diabetes mel-litus, and should only be undertaken on the advice of a physician. (The combination of these nutrients could negate insulin effectiveness.)
METHIONINE
An essential amino acid that helps in the breakdown of fats, methionine is a powerful antioxidant. Like cystine, it is another sulfur-containing amino acid, and helps protect the body from toxic substances as well as destructive free radicals. |
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