Gary Null, Ph.D.
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 This article reports on the case of a patient who experienced an allergic reaction to vitamin b12 which manifested itself in terms of eczematous and exanthematic skin lesions following long-term intake of high doses.
—I. Pevny, et al., "Vitamin B 12-(cyanocobalamin)-allergy," Hautarzt, 28(11), November 1977, p. 600-603.
¦ VITAMIN C
This article reports on the case of a patient receiving a single intravenous dose of 45 g of ascorbic acid for treatment of primary amyloidosis and the nephrotic syndrome who experienced acute oliguric renal failure.
—J.M. Lawton , et al. |
Henry Pasternak, D.V.M., C.V.A.
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 Though certain intestinal bacteria can produce vitamin b12, vitamin K, and B-complex factors, with rare exceptions, nearly all vitamins in food are either directly or indirectly produced by plants. Vitamin-rich whole foods are still the only source of virtually all the vitamins. Some of the best sources include seeds, nuts, whole grains, eggs, vegetables, yeasts and yeast extracts, liver and other organ meats, and fruits. In humans, clinical vitamin deficiencies are rare in industrialized countries such as the United States. |
Ralph Moss, PhD
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 Harmful effects have been mistakenly attributed to vitamin C, including hypoglycemia, rebound scurvy, infertility, mutagenesis [formation of mutations], and destruction of vitamin b12," wrote Mark Levine in the Journal of the American Medical Association in 1999. "Health professionals should recognize that vitamin C does not produce these effects."
(230)
The Food and Nutrition Board of the National Academy of Sciences' Institote of Medicine concurred. They are formulating new "dietary reference intakes" for the healthy U.S. population. |
Gary Null, Ph.D.
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| Liver Damage
Results of this study showed that the administration of 30 mg of SAMe six times per day coupled with 6000 gamma per day of vitamin b12 produced a significant improvements of biochemical parameters in patients with hepatic cirrhosis or various chronic hepatites.
—F. Miglio, et al., "Double-blind Studies of the Therapeutic Action of S-Adenosylmethionine (SAMe) in Oral Administration, in Liver Cirrhosis and other Chronic Hepatitides," Minerva Med, 66(33), May 2, 1975, p. 1595-1599. |
| THREONINE Seed 7,820—8,598 ppm THREONINE Sprout Seedling 370—3,886 ppm TYROSINE Seed 7,140—7,850 ppm TYROSINE Sprout Seedling 520—5,462 ppn URIDINE-5'-MONOPHOSPHATE Sprout Seedling
URIDINE-DIPHOSPHATE Sprout Seedling URIDINE-DIPHOSPHATE-GALACURONIC-
ACID Sprout Seedling URIDINE-DIPHOSPHATE-GLUCURONIC-
ACID Sprout Seedling URIDINE-DIPHOSPHATE-N-ACETYL-
GLUCOSAMINE Sprout Seedling UROCANIC-ACID Sprout Seedling VALINE Seed 12,370—13,600 ppm VALINE Sprout Seedling 1,300—13,655 ppm VERBASCOSE Seed 38,000 ppm vitamin b12 Seed VITAMIN B6 Seed 3.7—4.3 ppm
VITAMIN B6 Sprout Seedling 0. |
The Editors of Prevention Magazine Health Books
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 The amount of vitamin b12 recommended here is many times the Daily Value and should be taken only under medical supervision. Depending on the severity of your condition, your doctor may choose to administer B12 by injection.
Before prescribing a high dose of vitamin C, your doctor should determine how much of this nutrient you can tolerate. Some people experience diarrhea with amounts of more than 1,200 milligrams daily. For this reason, it's important that you discuss this therapy with your doctor.
If you are taking anticoagulant drugs, you should not take vitamin E supplements. |
Robert Hass, M.S.
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 Note to strict vegetarians: vitamin b12 is found only in animal products, fortified food products such as breakfast cereals, and vitamin supplements.)
Now, scientists are taking a hard look at homocysteine's involvement in other health problems. Cancer researchers are now wondering if homocysteine is involved in tumor growth. Scientists are also searching for links to diabetes, organ rejection, and some nerve disorders. Homocysteine may even cause problems in pregnancy. |
Carlton Fredericks, Ph.D.
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| This has been observed in women who take estrogen-based birth control pills, which are now known to cause deficiencies in Vitamin B6, vitamin b12, and folic acid.
I have seen administration of estrogen worsen the effects of nutritional inadequacy. I have watched symptoms of such dietary deficiencies intensify as women enter the high-estrogen phase of the menstrual cycle. This also happens during the latter part of pregnancy, when there is a pronounced rise in the body burden of female hormone. |
Robert Hass, M.S.
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| Since high-protein animal foods usually contain a poor supply of these heart-healthy nutrients (except vitamin b12), homocysteine in the blood increases the risk of heart attack and stroke.
• Protein from animal foods contains an amino-acid profile (individual amino acids bonded together form proteins) that can accelerate the loss of calcium and other minerals from the skeleton. Many animal-protein foods are relatively high in the sulfur-containing amino acids methionine and cysteine. |
| Since the elderly may have trouble absorbing adequate vitamin b12, many should take a B-complex vitamin supplement.
The Cancer—Heart Disease Connection
Cancer and heart disease may be kissing cousins. One theory holds that the plaque buildup that eventually blocks the blood flow in an artery arises from a tumor in the arterial wall. |
| Methylation: The combining of methyl groups (CH3-) derived from vitamin b12, folic acid, and dietary compounds, such as the amino acids L-methionine and L-cysteine, and betaine, with DNA (deoxyribonucleic acid). This coupling turns certain genes on or off, thereby preventing run-away cellular growth that can lead to cancer. Inadequate methylation of DNA can lead to tumor cell formation.
Mitochondria: The "power plants" inside cells where oxygen and nutrients are metabolized to water, carbon dioxide, and energy. |
| Cobalamin: See vitamin b12 (cobalamin).
Coenzyme Q10: A substance synthesized by the body responsible for the synthesis of adenosine triphosphate (ATP), the universal energy molecule. Research suggests that coenzyme Q10 acts as a fat-soluble free-radical neutralizer and helps regulate the electrical conduction system of the heart. |
Paul Pitchford
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 Even though cleanliness is of unquestionable value in food processing, its does halt the natural propagation of vitamin b12 in ferments.
Tempeh, a currently popular cultured soy product with origins in Indonesia, has some of the highest B12 content of any food (up to 15 micrograms of the vitamin in a 100-gram serving). When tempeh was introduced in America in the 1970s, it was generally produced by cottage industries, and B12 levels often ran a respectable four micrograms. |
| Symptoms of vitamin b12 deficiency do not always show—they can be masked by the B-complex vitamin folic acid. Folic acid and B12 have certain similar functions, and each requires the presence of the other in many of their activities.14 While folic acid alone seems to alleviate symptoms of B12 deficiency, an insidious process is actually underway as damage from insufficient B12 continues in the nervous system, with fewer outward symptoms. |
Gayle Reichler, M.S., R.D., C.D.N.
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 Also check your multivitamin to see if it has at least 4 mg of vitamin B6 and 8 micrograms of vitamin b12.
Omega-3 essential fatty acids can help lower cholesterol and reduce the risk for heart disease, as discussed in the Active Wellness Basic Food and Nutrition Guidelines. Although omega-3 supplements and vitamin E can help you, the wrong dosage may increase your risk for stroke. Therefore, be sure to consult your physician before taking fish-oil or vitamin E supplements. |
Gary Null, Ph.D.
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| Folic Acid and vitamin b12 in Vitiligo: A Nutritional Approach," Cutis, 50(1), July 1992, p. 39-42.
¦ VITAMIN C
Adrenal Function
Ascorbate's effects on the regulation of 11 beta-hydroxylase in culture were studied. In the absence of ACTH, 11 beta-hydroxylase activity declined with a half-time of approximately 40 hours. With the addition of 50 microM Cortisol, the half-time was reduced to approximately 6 hours. The rate of loss of 11 beta-hydroxylase activity in the presence of Cortisol was greatly reduced with the addition of 5 mM of ascorbate. |
Prevention Magazine
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 B12, 5 percent of the DV. vitamin b12, which is found almost solely in animal foods, is essential for healthy brain function. Get too little B12 and you may find yourself feeling fatigued and experiencing memory loss and other neurological problems.
Another B vitamin, B6, is critical for maintaining immunity. It's also necessary for making red blood cells and maintaining a healthy nervous system. Poultry provides between 0.2 and 0.5 milligram of vitamin B6, 10 to 25 percent of the DV.
Metal for Your Mettle
When knights went into battle, they donned suits of armor to make them stronger. |
Isadore Rosenfeld, M.D.
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 Sometimes a child with cystic fibrosis will bleed vigorously from a simple cut.) vitamin b12, though not a fat-soluble vitamin, is also often poorly absorbed in people with cystic fibrosis, resulting in the same blood and neurological complications that occur in pernicious anemia, a disease of B12 deficiency.
The pancreatic enzymes trypsin and chymotrypsin split dietary protein in food into its more digestible amino acid components. People with CF lack these enzymes too, so the protein in their diet goes the way of fat—undigested and unabsorbed. |
Prevention Magazine
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| DV. For vitamin b12, meat and shellfish are good choices. Three ounces of lean ground beef will provide 2 micrograms of vitamin Bi2, about a third of the DV. Clams are an incredible source, with 20 steamed clams providing 89 micrograms, 1,483 percent of the DV.
Maintaining the Flow
One way to alleviate memory problems is to get more blood to the brain, says Dr. Regelson. When adequate blood flow isn't maintained, the brain and memory begin performing poorly. |
| In addition, many cereals, pastas, and other packaged foods have been fortified with vitamin b12, she points out.
Most meats are full of other B vitamins as well. They generally provide 10 to 20 percent of the DV for B-complex vitamins: riboflavin (essential for tissue repair), vitamin B6 (needed for immunity), niacin (vital for skin, nerves, and digestion), vert blood sugar into energy).
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Grilled foods taste great, but for a long time researchers have worried about their safety. |
Neal Barnard, M.D.
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 This could include any common multivitamin, fortified soymilk or cereals, or a vitamin b12 supplement of 5 meg or more per day.
5. If nerve pains continue, try vitamin B6, 50-150 mg per day, in consultation with your physician, who can monitor your progress.
DOES COW'S MILK CAUSE DIABETES?
Cow's milk has come under scrutiny as a possible cause of childhood-onset diabetes. Many studies have suggested that cow's milk proteins elicit the production of antibodies that can damage the insulin-producing cells in the pancreas. |
Sharol Tilgner, N.D.
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 Avoid trauma to the mucous membranes of the mouth.
• vitamin b12, folic acid and iron deficiencies should be addressed if a factor.
Profiles of herbs used in this formula:
Licorice, Glycyrrhizaglabra, is soothing to the muocus membranes. It is anti-inflammatory and healing.
139-141,144,146
Peppermint essential oil, Mentha piperita, relieves the pain and inflammation associated with canker sores. |
| Dong quai's constituents include vitamin b12 and E, biotin, nicotinic acid, folic acid and folinic acid.
Contraindications: Due to furocoumarin content, it is contraindicated when taking blood-thinning agents.400 The furocoumarins also sensitize the skin to the sun and can increase the chance of sunburn. 11 Since it is a uterine vasodilatory, it may worsen heavy clotted menses. It may also aggravate gastroesophageal reflux due to the gastric stimulating effects. |
Neal Barnard, M.D.
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| Animal products contain vitamin b12 because bacteria in animals' intestines produce it, and it is then absorbed into their tissues. However, these products do much more harm than good and are not recommended.
You will find B12 in enriched breakfast cereals and many soymilk products. It may be listed by its chemical name, cobalamin or cyanocobal-amin. Red Star nutritional yeast, which is sometimes used to add a cheeselike flavor to foods, is naturally enriched in Bi2. |
Prevention Magazine
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| But you can get plenty of vitamin b12 by eating foods fortified with this nutrient, such as fortified cereals, fortified soy milk, or B12-enriched nutritional yeast.
BPsAised Vegetable m edley
16
1
172 1/4 11/2 teaspoons olive oil medium potatoes, cut into large chunks ounces small button mushrooms baby carrots package (9 ounces) frozen artichoke hearts cloves garlic, sliced cups vegetable broth or water teaspoon salt tablespoons minced fresh dill Ground black pepper
Per serving calories 181 total fat 5.3 g. saturated fat 0.8 g. cholesterol 0 mg. sodium 187 mg. dietary fiber 7.1 g. |
Glenn W. Geelhoed, M.D. and Jean Barilla, M.S.
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 That's why, if you are prone to canker sores, you might want to add these foods to your diet:
¦ Steamed clams, oysters and mussels (for vitamin b12)
¦ Peas, beans, wheat germ and lentils (for folic acid)
¦ Fortified cereals, lean cuts of beef and tofu (for iron)
A vitamin B-complex supplement (providing 100 milligrams of each of the B vitamins) may also help. And to treat canker sores once they've developed, try some of the following tried-and-true natural remedies. burnet Some herbalists recommend burnet to help heal mouth ulcers. |
Neal Barnard, M.D.
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| In addition to supplying folic acid and zinc, which are low in some people with sickle-cell disease, it also supplies vitamin b12, which is missing from grains, beans, vegetables, and fruits.3
Iron supplements should be used only if prescribed by your physician. While some people with sickle-cell disease are low in iron, others are iron-overloaded, particularly if they have had numerous blood transfusions.3 Guidelines to help you interpret your iron level test are given on page 91. |
Ronald L. Hoffman, M.D.
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 Most people who eat fish, chicken, eggs, and dairy foods will get sufficient vitamin b12 from their diet.
Calcium deficiencies are common in elderly people, and chronically low levels of calcium are often involved in disorders of memory and learning. Older memories, which are more widely "distributed" throughout the brain, are less vulnerable to disruption than more localized recent memories. Recent studies cited in the British medical journal The Lancet suggest that calcium deficiency may be a more important factor in the development of Alzheimer's disease than aluminum poisoning. |
Prevention Magazine
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| Clams are a top performer: 20 small steamed clams provide an astonishing 89 micrograms of vitamin b12, 1,483 percent of the DV.
As bones get older, it's essential to get extra calcium to prevent them from becoming brittle, says Dr. Nitzke. "Many people believe that they can't eat dairy foods because they're 'lactose intolerant,' but in fact, most people can eat moderate amounts of dairy without trouble," she says.
Low-fat milk and skim-milk cheese and yogurt are your best sources of this bone-building nutrient. |
Ronald L. Hoffman, M.D.
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| In both sexes it's important to assess vitamin b12 levels. Deficiencies can be devastating and can cause symptoms that resemble those of Alzheimer's disease, to say nothing of weakness and fatigue. Folic acid is an important cancer-protective nutrient that's good to check.
• New tests to assess antioxidant levels in the bloodstream and measure the extent of free-radical damage in the body. These can provide a very strong indicator of someone's overall health and long-term prognosis. They can provide a definite basis on which to recommend antioxidants. |
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