| Although synthetic vitamin e is not harmful and does have antioxidant value, I prefer the natural form.
I usually recommend 50-100 mg per day for people who have immune system disorders or fatigue, or if they are over 40 years old, when production of CoQIO is significantly lower. If they have heart problems or cancer, I usually use higher doses, ranging from 100 to 300 mg per day, and sometimes even more.
Vitamin K
Although I have not used vitamin K as a supplement, some of my colleagues do, and it is worth mentioning. | Sheldon Saul Hendler and David Rorvik See book keywords and concepts | In the ATBC study of Finnish smokers, low-dose synthetic vitamin e (50 milligrams daily) reduced the incidence of prostate cancer by a significant 32% and prostate cancer deaths by a significant 41%. This unexpected result was sufficiently impressive that the National Cancer Institute is considering a follow-up study.
Reduction in prostate cancer incidence became evident in the ATBC study within two years of beginning supplementation. | Dr. Julian Whitaker See book keywords and concepts | | Avoid synthetic vitamin e, which is labeled as dl-alpha tocopherol (or dl-alpha tocopheryl).
Vitamin C
While vitamin E is the pre-eminent antioxidant of the fatty portions of the cells, vitamin C is the top gun in the watery areas. Vitamin C is obviously important to the brain and central nervous system because its concentration in the brain is fifteen times higher than elsewhere in the body. In addition to its antioxidant activity, vitamin C is involved in the production of several neurotransmitters, including acetylcholine, dopamine, and norepinephrine. | Gary Null See book keywords and concepts | NATURAL OR synthetic vitamin e?
But which supplement should you take? There are so many. Natural or synthetic E? And how much? Here are five facts you should know about taking vitamin E supplements.
• Read the labels. Try to choose a supplement that lists "pure alpha-tocopherol," which should be easy in a good pharmacy or health food store. Why? Because alpha-tocopherol is the most active biologically and is better than mixed tocopherols. Also, the effectiveness of the vitamin E in a mixed tocopherol preparation may be diluted,
• Some people have trouble digesting fats. | Robert S. McCaleb, Evelyn Leigh, and Krista Morien See book keywords and concepts | In this randomized, double-blind, placebo-controlled trial, participants took 2 bilberry tablets twice daily (each containing 180 mg bilberry extract) and 100 mg synthetic vitamin e or placebo for 4 months. At the conclusion of the 4-month trial, 97 percent of the affected eyes in the active group showed no progression in lens opacity, whereas 3 percent worsened. In the placebo group, 77 percent had no progression of cataracts, whereas 23 percent worsened. No adverse effects were reported. | Dr. Gary Null See book keywords and concepts | D-alpha tocopherol is also preferred over synthetic vitamin e. Generally, 400 IU per day should be taken in the beginning. The dosage can be gradually increased to 600 IU, although some women may need up to 800 IU.
Zinc. This mineral supports ovarian function. A good source is zinc picolinate. It can also be taken as an amino acid chelate or as zinc methionine. Twenty-five to 30 mg per day is generally needed.
B complex. B-complex vitamins are important throughout life, but there is an extra need for these during menopause. They can be obtained from whole grains, and green vegetables. | | Avoid synthetic vitamin e (dl-alpha).
Beta carotene. 25,000 IU per meal. Helps slow down aging and lessens cancer risk. Nontoxic, since the body must convert beta carotenes into vitamin A and will not convert more than it can use.
Vitamin A. 1,000-3.000 IU per meal. Blood tests will determine whether or not a person is getting too much vitamin A. which can be toxic.
Selenium. 100 meg per meal. One of the causes of premature aging and even death, particularly in professional athletes, is cardiomyopathy, an enlargement of the heart. This is usually associated with selenium deficiency. |
Natural Prescriptions: Dr. Giller's Natural Treatments & Vitamin Therapies For Over 100 Common AilmentsRobert M. Giller, M.D. See book keywords and concepts | | The synthetic vitamin e was found ineffective.)
Vitamin A, taken in high doses, also stimulates complete or partial remission of cystic mastitis. However, some people developed headaches in high-dose vitamin A studies and had to withdraw. Beta-carotene, with similar activity, has been used by my patients with success.
Primrose oil has been used successfully in Europe to reduce the size of cysts, and is now available in health food stores in the United States. I recommend it regularly. | Dr. Gary Null See book keywords and concepts | Avoid synthetic vitamin e (dl-alpha).
Beta carotene. 25,000 IU per meal. Helps slow down aging and lessens cancer risk. Nontoxic, since the body must convert beta carotenes into vitamin A and will not convert more than it can use.
Vitamin A. 1,000?,000 IU per meal. Blood tests will determine whether or not a person is getting too much vitamin A, which can be toxic.
Selenium. 100 meg per meal. One of the causes of premature aging and even death, particularly in professional athletes, is cardiomyopathy, an enlargement of the heart. This is usually associated with selenium deficiency. | Sheldon Saul Hendler and David Rorvik See book keywords and concepts | For establishing RDAs of vitamin E, alpha-tocopherol is defined as the natural RRR-alpha-tocopherol and the 2R-stereoisomers of synthetic vitamin e (found in supplements and fortified foods), RRR-, RSR-, RRS-, and RSS-alpha-tocopherols. The 2S-stereoiso-mers are excluded by this definition. All forms of supplemental vitamin E are included in calculating the Tolerable Upper Intake Level (UL).
The new RDA for vitamin E (again, defined as only alpha-tocopherol) for both men and women is 15 milligrams daily, To convert from milligrams to International Units (UI), the conversion factor is 1.49. | | The greater potency of natural-source vitamin E is widely recognized, and some studies have indicated that natural-source alpha-tocopherol is at least twice as bioavaila-ble as synthetic vitamin e.
Some other researchers said the GISSI trial made too little of the reduction in deaths apparently attributable to vitamin E. Two researchers stated that "cardiovascular mortality was significantly reduced by vitamin E in GISSI, and the effect on overall survival showed a very favorable trend." Others argued that a longer follow-up period was needed. The GISSI trial lasted for 3.5 years. | | In the GISSI-Prevenzione trial, 11,324 Italian survivors of myocardial infarction were given 300 milligrams of synthetic vitamin e daily or a mixture of n-3 polyunsaturated fatty acids (PUFA) in a combination of docosahexaenoate (DHA) and eicosapentaenoate (EPA), or both the vitamin E and the n-3 PUFA combination, or neither. The primary end points were nonfatal myocardial infarction, stroke and death. | | In the Linxian China study, supplemental beta-carotene (15 milligrams daily), synthetic vitamin e (30 IUs daily) and selenium (50 micrograms daily) significantly protected against total mortality and total cancer (which was the primary focus of the study) and non-significantly protected against cerebrovascular disease. The vitamin E dose used in this study was even smaller than that used in the ATBC study. In both cases, synthetic alpha-tocopherol was used. | | Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin e. Am J Clin Nutr. 1998; 67:669-684.
Delcourt C, Cristol J-P, Tessier F, et al. Age-related macular degeneration and antioxidant status in the POLA study. Arch Opthalmol. 1999; 117:1384-1390.
Dietary Reference Intakes for Vitamin C, Vitamin E. Selenium and Carotenoids. Washington, D.C.: National Academy Press; 2000.
Dowd P, Zheng ZB. On the mechanism of the anticlotting action of vitamin E quinone. Proc Natl Acad Sci USA. 1995; 92:8171-8175. | Gary Null See book keywords and concepts | The difference is this: nature's own vitamin E contains variety, like nature itself. synthetic vitamin e looks machine-made, which it is. Nature's design, as in so many other cases, is a hard one on which to improve. If you had to choose between a vegetable grown in earth and one grown in a factory, which would you choose? The answer is obvious. Why cheat yourself when choosing a vitamin supplement?
When reading the labels on a bottle of vitamin E supplements, how can you tell the natural form from the synthetic?
• Vitamin E is natural if it begins with a "d. | Michael Janson, M.D. See book keywords and concepts | Vitamin E
Natural vitamin E (as i-alpha tocopherol plus the mixed tocopherols—beta, gamma and delta) is a good biological antioxidant, protecting you from the ravages of free-radical pathology, heart disease, cancer, and aging. synthetic vitamin e (dZ-alpha) is about 50% less active than the natural form. Be careful when reading the label, as that little "I" after the "d" may be obscure. The forms other than alpha are not used to characterize the potency of the capsules of vitamin E, but they are active, and the gamma form may be at least as important as the alpha. | Robert Hass, M.S. See book keywords and concepts | E, 1 milligram equals 1.1 international unit.
A recent study that examined the vitamin C and vitamin E intake of 11,178 senior citizens revealed that the effects of these two vitamins were combined; risk of death from all diseases and especially coronary artery disease was reduced by 34% and 63% respectively.
The most telling finding of this recent study was that people who took a low-potency "once a day"-type multiple vitamin supplement fared no better than those taking nothing at all. |
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