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Lignan

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PDR for Nutritional Supplements

Sheldon Saul Hendler and David Rorvik
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MECHANISM OF ACTION SDG, as well as its mammalian lignan metabolites, enterolactone (EL) and enterodiol (ED), have weak estrogenic activity as measured in in vivo and in vitro assays. SDG, EL and ED have a number of antioxidant activities, including inhibition of lipid peroxidation and scavenging of hydroxy radicals. SDG also has anti-platelet-activation factor (PAF) activity. PAF can induce the release of reactive oxygen species from neutrophils.

The Natural Guide to Medicinal Plants and Herbs

Frantisek Stary
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The medicinally important flavonol rutin was isolated for the first time from Rue, hence its name. The effect of strong doses of the large group of active principles is toxic and therefore increasing the dosage above the tested limit is dangerous. The drug has antispasmodic properties and is used to relieve gall bladder attacks and menstrual pains. Also well known is the drug's sedative action when it is administered in therapeutic doses to treat hot flushes during menopause, subjective complaints of nervous origin, and neurovegetative disorders.

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