| Spanka M, Koehrle J, Irmscher K, Hesch RD. flavonoids specifically inhibit iodothyroninedeiodinase in rat hepatocytes. Prog Clin Biol Res 1988;280:341-44. urtnoioaosuppiementation: iodine butticiency ot the Whole Human Body
Guy E. Abraham (MD), Former Professor of Obstetrics, Gynecology and Endocrinology at The UCLA of School of Medicine, Jorge D. Flechas (MD), and John C. Hakala (R.Ph)
(Reprinted by permission of the authors)
I. INTRODUCTION
The essential trace element iodine (I) is the only one required for and in the synthesis of hormones. |
| The plant contains glycosides and flavonoids, but the mechanism of action for hyperthyroidism has not been determined. According to the clinical report, in using this remedy during a 3-year period, the doctors found it safe and reliable. No toxicity was revealed upon examination of liver function, potassium and sodium levels, and blood sugar.
The herb huangyaozi is a common ingredient in formulas for hyperthyroidism, and it has been used in individual cases as a sole ingredient. |
Russell L. Blaylock, M.D.
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 Also, there are over forty carotenoids and five thousand flavonoids from plants in the human diet that act as antioxidants.
Each antioxidant acts in a different place in the cells and tissues. For example, vitamin C is concentrated in the blood plasma, connective tissues, and within the cytoplasm of the cell. Vitamin E components are dissolved in the fatty parts of the cell such as the membranes and are not usually concentrated within the watery parts of the cell. Vitamin E is also an important part of the LDL cholesterol molecule. |
Phyllis A. Balch, CNC
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 There are also a number of phytochemicals and nutrients that act as antioxidants, including vitamin A, beta-carotene and other carotenoids, flavonoids, vitamins C and E, and the mineral selenium. Researchers have recently found that eggplant contains high levels of chlorogenic acid, which has proven to be a highly effective antioxidant. Another antioxidant is the hormone melatonin, which is a powerful free radical neutralizer. Certain herbs have antioxidant properties as well. |
Gabriel Cousens, M.D.
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 Wine has a whole lot of flavonoids. Red wine also has a number of phenolics, the most important being resveratrol and quercetin, which alter gene expression and enhance phenotypic expression to protect against blood clot formation as in heart disease. Resveratrol also has certain anti-aging qualities that are recently being touted to mimic the calorie restriction effect. However, red wine also has the downside of being alcohol. Alcohol does many things to disregulate and undermine healthy gene expression, particularly in the neurotransmitter systems, as well as other systems in the body. |
KC Craichy
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 The best sources include tea leaves, oranges, citrus fruit, apples, onions, red grapes, berries, and pine bark.19 Flavonoids:
¦ Improve memory and concentration and are used to treat attention-deficit disorder.
¦ Are powerful free-radical scavengers that can boost the effectiveness of Vitamin C in the antioxidant network.
¦ Regulate nitric oxide, a potent free radical that is a regulator of blood flow
¦ Keep your heart healthy in three important ways. They prevent blood clots, protect against oxidation of LDL cholesterol, and lower high blood pressure.
» Improve sexual function in men. |
Gabriel Cousens, M.D.
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| One important part of this anti-aging process is a diet high in antioxidants - a diet that's high in carotenoids, flavonoids, zinc, manganese, copper, and vitamins E, C, and A.
The collector's edition of Life Extension 2004 reports that the phy-tonutrient resveratrol, which activates sirtuin genes, has been found by researchers at Harvard Medical School and BIOMOL Research Laboratories to activate a "longevity gene" in yeast that lengthens lifespan by 70 percent. It seems to activate one of the same genes as caloric restriction (discussed in Chapter 22). |
| Polyphenols are broken down to subclasses such as flavonoids and proanthocyanidins. Resveratrol is found in organic grapes, pine trees, and other plants such as polygonnum cuspidatum. This expansion of information on resveratrol helps to make the point of the role of phytonutrients in gene control and as antioxidants. When we cook our food, many of the actions of these phytonutrients are compromised or entirely lost. The effects of free radical damage are seen throughout the whole body. |
James F. Balch, M.D. and Mark Stengler, N.D.
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 It improves blood flow and contains flavonoids that support eye structure and function.
Super Prescription #7 Chromium
Take 250 to 500 meg twice daily. It is particularly important for people with diabetes to supplement for blood-sugar balance and the prevention of glaucoma.
General Recommendations
Grape seed extract or maritime pine bark improves circulation. Take 100 to 200 mg daily.
Rutin is a bioflavonoid that has been shown in older studies to help glaucoma. Take 20 mg three times daily. |
| Various flavonoids, such as rutin and hes-peridin, have been shown to be effective in treating hemorrhoids. They reduce swelling and prevent bleeding.
Super Prescription #7 Bilberry (Vaccinium myrtillus)
Take a standardized extract containing 25 percent anthocyanosides at 160 mg twice daily. Bilberry improves circulation and strengthens capillary walls. study of fifty-one pregnant women found that supplementation of bilberry significantly improved the pain, the burning, and the itching associated with their hemorrhoids. |
| Various flavonoids, such as rutin and hes-peridin, have been shown to be effective in treating hemorrhoids. They reduce swelling and prevent bleeding.
Super Prescription #7 Greens drink
Consume a greens drink that contains a blend of super green foods, such as chlorella, spirulina, and so on. It provides fiber. Take as directed on the container.
Homeopathy
Pick the remedy that best matches your symptoms in this section. Take a 6x, 12x, 6C, 12C, or 30C potency twice daily for two weeks to see if there are any positive results. |
| Berries that have a bluish-red color—cherries, blueberries, and blackberries, for example—are rich in the flavonoids you need so enjoy them often as snacks or dessert. Buckwheat, as a food and in tea form, is a good source of a flavonoid called rutin, which increases the strength of capillaries. Use it in whole-grain pancakes or breads.
To improve circulation, flavor your meals with garlic, onions, ginger, or cayenne pepper.
Vitamin E is good for the circulation and also helps prevent blood clots. Wheat germ is an excellent source, as are soybeans and leafy greens. |
| Various flavonoids, such as rutin and hes-peridin, have been shown to be effective as accessory nutrients in treating varicose veins.
Super Prescription #5 Bilberry (Vaccinium myrtillus)
Take a standardized extract containing 25 percent anthocyanosides at 160 mg twice daily. Bilberry improves the circulation and strengthens capillary walls.
Super Prescription #6 Vitamin E
Take 400 IU of a mixed complex twice daily. Vitamin E acts as a natural blood thinner, to promote blood flow and reduce inflammation of the veins. |
| This supplement contains a class of flavonoids known as proanthocyanidins. Grape seed is mainly used as an antioxidant and to improve the stability of collagen and elastin, two substances that are important for healthy skin, joints, ligaments, tendons, and blood vessels. It is also used to improve microcirculation throughout the body.
Indications: Antioxidant support Bruising
Macular degeneration
Retinopathy
Varicose veins Precautions: No side effects have been reported. Dosage: Take 50 to 300 mg daily. |
Ann M. Coulston and Carol J. Boushey
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 SU.VI.MAX. study [57-60]. Dietary intakes were estimated using six 24-hour dietary records collected during the course of 1 year. In women, flavonoid-rich food consumption was associated with decreased systolic blood pressure and a decreased risk for CVD; this relationship was not observed in men. The lack of an effect in men could be attributed to the men's higher risk for CVD; inconsistencies in dietary reporting and measuring of flavonoid consumption also could contribute to this discrepancy. However, this study found that, after 7. |
Jonny Bowden, Ph.D., C.N.S.
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 Orange Therapy
Oranges contain limonoids, phytochemicals abundant in citrus fruit that account for the scent of fresh lemon and orange peels. (Many of the plants used in traditional healing, such as the neem plant, are rich in limonoids.) Currently limonoids are under investigation for a wide variety of therapeutic effects such as antiviral, antifungal, antibacterial, antineoplastic, and antimalarial. In laboratory tests with animals and with human cells, citrus limonoids have been shown to help fight cancers of the mouth, skin, lung, breast, stomach, and colon. |
John Heinerman
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 Scientists who've evaluated the herb extensively now believe it is the flavonoids present in the plant which account for its dramatic anti-cancer activity. One study published in Cancer Research (48 (22): 6257-61. 1988) found that the total flavonoids from the blossoms inhibited by 40% the activity of a common laboratory carcinogen called benzopyrene, a compound always found in charcoal-broiled foods. An even earlier study in the same journal (30-.1922-25, July 1970) observed that one of these flavonoids. |
Ben-Erik van Wyk
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 Various organic compounds such as phenols and flavonoids also contribute to the nutritional value by their protective role against cancer and their antioxidant and venotonic effects.
Fruits are variously processed into jams and juices or may be canned or dried. Dried fruits have a high food value because they yield at least four times more calories than fresh fruits. This makes them ideal as a health food and energy source for young children. Sulphur has been used as a preservative for dried fruit but with improved processing methods it is possible to avoid all preservatives. |
Mike Adams
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 In the past, phytochemicals were classified as vitamins: flavonoids were known as vitamin P, indoles and glucosi-nolates were called vitamin U, and so on. But they lost their status as vitamins because specific deficiency symptoms could not be established. Today, phytochemicals are classified according to their functions as well as individual physical and chemical characteristics of the molecules.
- Mary Dan Eades, M.D., The Doctor's Complete Guide to Vitamins and Minerals
Foods that contain phytochemicals
So where do you find phytochemicals on the menu? |
The Editors of FC&A
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| You'll not only get lots of vitamin C, you'll be loading up on other antioxidants, like vitamin E, beta carotene, and a variety of flavonoids.
Create a salad for
Apples, oranges, bananas, strawberries, and blueberries are some of the fruits and berries also loaded avocado s\\ces and with antioxidants. Enjoy them on mandarin oranges on cereal, in salads, or by themselves a bed of greens. Top it as snacks. When possible, eat the off with a few slivered skins of fruits and vegetables, too. almonds and a low-fat tt, ^ cu jj vinaigrette dressing. |
Ben-Erik van Wyk
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| The health properties are mainly ascribed to the high levels of anthocyanins, polyphenols and flavonoids that act as antioxidants and venotonics (to strengthen arteries and veins).
Artemisia absinthium wormwood • absinthe
Wormwood Mugwort
Description Wormwood is an aromatic perennial herb of up to 1 m in height, with silky, silvery, pinnately divided leaves and small yellowish flower heads borne in large numbers on the branch ends. Closely related species such as African wormwood (A. afra) and the two European species known as southernwood [A. abrotanum) and mugwort (A. |
Leslie Taylor, ND
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 Many biologically active compounds have been discovered in anamu, including flavonoids, triterpenes, steroids, and sulfur compounds. Anamu contains a specific sulfur compound named dibenzyl trisulfide. In a plant-screening program at the University of Illinois at Chicago that evaluated more than 1,400 plant extracts as novel therapies for the prevention and treatment of cancer, anamu was one of thirty-four plants identified with active properties against cancer. The researchers reported that dibenzyl trisulfide was one of two of the active compounds in anamu with anticancerous actions. |
Phyllis A. Balch, CNC
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| This liquid supplement contains extracts of common ash, aspen, and goldenrod; the key compounds include salicylic acid derivatives, phenolic acid, flavonoids, and triterpene saponins. Phytodolor is intended to support muscle and joint function without causing stomach irritation, as do many other products used for the relief of arthritis and similar disorders.
• PreNatal Care from Natrol, Inc. This is a combination supplement designed for pregnant women and nursing mothers. |
Ben-Erik van Wyk
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| The main classes of compounds are alkaloids, antioxidants, flavonoids, sulphur-containing substances and tannins. Alkaloids such as caffeine (found in tea and coffee) and quinine (found in tonic water) are bitter substances that stimulate the flow of gastric juices (the so-called amarum effect), thereby improving digestion. They are also stimulants that increase the heart rate and enhance the production of urine. Antioxidants comprise a wide diversity of compounds, including several vitamins as discussed above (mainly vitamins A, C and E). |
Mike Adams
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| Their phytochemical content also includes the carotenoids and flavonoids, the most powerful of the antioxidants.
Researchers have suggested that the ubiquitous presence of sea vegetables in the Japanese diet may be why the incidence of breast cancer in Japanese women is one-sixth that in American women. Sea vegetables have been shown in the test tube and in laboratory animals to suppress colon cancer and to boost the immune system. A drink of broth made from kombu, a brown alga, reduces hypertension and can help prevent strokes. |
| They are isolated from plants and are known technically as anthocyanosides, limonoids, glucarates, phenolic acids, flavonoids, coumahns, polyacetylenes and carotenoids
- Francisco Contreras, M.D., Health in the 21st Century
It's important to remember that phytochemicals are not vitamins, nor do they function exactly like vitamins in the human body. For one thing, there's no such thing as an essential phytochemical in the same way there are recognized essential vitamins. |
Phyllis A. Balch, CNC
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| Fresh fruits and vegetables not only supply valuable vitamins and minerals, but are rich in compounds called flavonoids, many of which scavenge and neutralize dangerous free radicals.
Q Avoid processed foods and all foods that create stress on the system, such as artificial sweeteners, carbonated soft drinks, chocolate, eggs, fried foods, junk foods, pork, red meat, sugar, white flour products, foods containing preservatives or heavy spices, and chips and similar snack foods.
Q Eliminate dairy products from your diet for three weeks. |
Mike Adams
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| Phytosterols in whole grains, legumes, and soy quite literally compete with the estrogens that promote cancer; while they don't destroy these cancer-causing agents, they do deflect them from their path. flavonoids in just about all fruits and vegetables — and in wine — block carcinogens' access to cells and suppress malignant changes in cells.
- Stephanie Beling, M.D., Power Foods
As you can see, many people view the phytochemicals in plants as nothing more than a natural source for drugs. |
David Wolfe
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 Raw cacao beans, perhaps the most concentrated source of antioxidants found in any food, contain heart-friendly catechin and epicatechin flavonoids.
Up until now, what had been overlooked is that raw plant fat sources are always also powerful antioxidants. Raw plant fats have long-chain fatty acids which help protect cell membranes from oxidation. Raw plant fats deactivate free radicals by giving them electrons. Raw plant fats are loaded with spare electrons and having spare electrons equates into achieving longevity. |
Mike Adams
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| The following are just some of the flavonoids you should at least know a little about because they can do a lot for your health!
- Earl Mindell's Vitamin Bible
And take a look at all the scientific-sounding names given to the various classes of identified phytochemicals:
Phytochemicals can do more than defend against cancer; they can also counterattack. Indol
- 3-carbinol found in cabbage, cauliflower, and other cruciferous vegetables, triggers enzymes that keep the form of estrogen linked to breast cancer from predominating. |
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