Hyla Cass See book keywords and concepts | Other reports suggest reductions in omega-3 fatty acids and a 30 percent reduction in body levels of carotenoids, a class of antioxidant nutrients that includes beta-carotene.
Needed supplements: Take vitamin A (20,000 IU), vitamin E (100 milligrams [mg] in tocotrienol form, see below for more information), vitamin D (400-2,000 IU), folic acid (400 micrograms [meg]), vitamin K (80 meg), calcium (1,000 mg), iron (15 mg, if you're premenopausal), magnesium (400-600 mg), vitamin B12 (200 meg), and zinc (25 mg), and omega-3 fatty acids (1,000-3,000 mg). | Elaine Magee See book keywords and concepts | But the harm may be in taking large amounts of beta-carotene all by itself, via supplements; numerous past studies indicated that people who eat the most vegetables and fruit and foods rich in carotenoids have the lowest risk of lung cancer.
A similar story cropped up a few years later with vitamin E supplements. "High doses of vitamin E were found to raise the risk of dying," read the headlines in 2004. According to a pooled statistical analysis of 19 studies, people taking 400 IU or more a day had about a 5 percent higher death rate than those who didn't take that much vitamin E. | David Steinman See book keywords and concepts | Instead of providing synthetic beta-carotene, its nutritional supplements, for example, utilize carotenoid-rich sources such as marigold that are then potentiated with the use of beneficial bacteria; In addition, New Chapter was the first nutrition company to receive government certification for its all organic herbal formulas. Thus, New Chapter helps the business patrons to fulfill its mission by offering nutritional formulas that truly embody the concept that nature trumps the laboratory.
We passed through a small town and ate lunch. | Elaine Magee See book keywords and concepts | Soy milk, regular, 1 c
40
10
140
Tofu, firm, 4 oz, uncooked
38
9
120
Textured soy protein, % c, cooked
35
11
59
Soy milk, light, 1 c
20
4
100
Isolated soy protein, V4 c
14
6
30
Soy concentrates, 1 oz, dry
12
17
94
CAROTENOID FAMILY
You may have heard news bites about a particular carotene, beta-carotene, in recent years. Well, it turns out that we probably should be inviting the whole family of carotenoids to dinner! Some researchers suggest that mixtures of carotenoids exhibit more antioxidant activity than each of the carotenoids does by itself. | | The researchers suspect that much of the protection comes from a group of phytochemicals known as polyphenols, because the results persisted after they accounted for intake of other known Alzheimer-fighting nutrients, including vitamins E, C, and beta-carotene. Other laboratory studies have also confirmed that some polyphenols from juices appear to offer brain cells stronger protection than antioxidant vitamins do.
How could polyphenols protect against Alzheimer's disease? | | To Reduce Effects of LDL Cholesterol: þGarlic + onions, which contain organosulfur phytochemicals þOat phytochemicals + vitamin C þAlmond skin + vitamins C and E þVitamin C and E + beta-carotene þCitrus extracts + vitamin C in citrus þSoy protein þSoy (phytoestrogens) + vitamin C in citrus þGround flaxseed (highest food source for lignans) þRed wine (polyphenols) þGrapefruit (part of a low-fat heart-healthy diet) þGreen tea
To Reduce LDL Blood Levels: þThe Portfolio plan (may reduce LDL by 30 percent) þNuts þGround flaxseed
(continued on page 210)
Putting Synergy Super Foods to the Test! | Ann N. Martin See book keywords and concepts | Vitamin A, both beta-carotene and retinol, maintains healthy coat and skin, promotes bone growth, protects against infection, and aids in the treatment of eye disorders. Vitamin A deficiencies result in night blindness, susceptibility to infections, dryness and itching, and poor growrh and development.
Vitamin B-l (Thiamine)The B vitamins are water-soluble but, as with all vitamins and minerals, do not go overboard. Vitamin B-l maintains normal function of the nervous system, and improves brain power in pets according to Wendell Belfield, DVM. | Ann M. Coulston and Carol J. Boushey See book keywords and concepts | Dietary and serum alpha-tocopherol, beta-carotene and retinol, and risk for colorectal cancer in male smokers. Eur. J. Clin. Nutr. 56, 615-621.
85. Wakai, K, Suzuki, K., Ito, Y., et al. (2005). Serum carotenoids, retinol, and tocopherols, and colorectal cancer risk in a Japanese cohort: Effect modification by sex for carotenoids. Nutr. Cancer 51, 13-24.
86. Le Marchand, L., Franke, A. A., Custer, L., Wilkens, L. R., and Cooney, R. V. (1997). Lifestyle and nutritional correlates of cytochrome CYP1A2 activity: Inverse associations with plasma lutein and alpha-tocopherol. | | Refined grains 1.1-2.0 beta-carotene -1.0
0.6-0.8
0.8-1.0
Older case-control studies and those that did not adjust for total energy more likely to report associations.
Many cohort and case-control studies observed no increased risk.
Most case-control and cohort studies report reduced risk at high levels of fiber intake.
Older case-control studies observed risk; newer cohort studies are less positive.
No consistent association
Many studies support inverse association.
Most studies suggest an increase in risk. | | Data from 11 of these studies allowed analysis of beta-carotene intake, which was significantly inversely associated with risk (RR 0.82, 95% CI 0.76, 0.91 for approximately >7000 versus < 1000 pg/day). Results from this meta-analysis are very similar to a summary based on 19 case-control and three cohort studies reported in 1997 [118], which found at least a 25% reduction in risk in the majority of the studies and greater consistency for vegetable compared to fruit intake. | | In addition, in the Australian Polyp Study [74] higher levels of beta-carotene were associated with greater recurrence of large polyps. Increased vitamin C, on the other hand [17], was associated with a marked decrease in colon cancer risk (OR 0.5; 95% CI 0.3-0.9).
Carotenoids, long recognized for their antioxidant properties, are of increasing interest in relation to cancer because of their effect on regulation of cell growth and modulation of gene expression, as well as their possible effect on immune response [81]. | | Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and Retinol Efficacy Trial. J. Natl. Cancer Inst. 88, 1550-1559.
79. Alpha Tocopherol Beta Carotene Cancer Prevention Study Group. (1994). The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N. Engl. J. Med. 330, 1029-1035.
80. Hennekens, C. H., Buring, J. E., Manson, J. E., et al. (1996). | Neal D. Barnard and Bryanna Clark Grogan See book keywords and concepts | Fruits and vegetables are not only cholesterol free and very low in fat; their beta-carotene, vitamin C, and vitamin E can actually reduce the damaging effects of cholesterol in your blood.13 Here's why.
As cholesterol particles glide along in your bloodstream, those that enter artery walls and cause plaque buildup are the ones that have become slightly damaged, or oxidized. beta-carotene, vitamin C, and vitamin E actually protect the cholesterol particles from damage so they go on their merry way without harming you. | Mark Sircus See book keywords and concepts | Selenium, especially when used in conjunction with vitamin C, vitamin E and beta-carotene, works to block chemical reactions that create free radicals in the body (which can damage DNA and cause degenerative change in cells, leading to cancer). Selenium also binds strongly with mercury, protecting us from its damaging effects.
Selenium helps stop damaged DNA molecules from reproducing, meaning that it acts to prevent tumors from developing. "It (selenium) contributes towards the death of cancerous and precancer cells. | J. Douglas Bremner See book keywords and concepts | In fact, if anything, there was a slight increase in mortality, although only about 2%, which is less than that for vitamin A and beta-carotene.
One study by Waters and colleagues of vitamin E combined with vitamin C showed that vitamins actually accelerated the progression of thickening of the coronary arteries and doubled the risk of dying of heart disease. | | Looking at all these studies together, there is an increased risk of heart disease with vitamin A and beta-carotene associated with a 29% increase in mortality when the two are combined.36
Trials for vitamin E have not shown that it prevents heart disease,37"40 with the exception of one study showing a modest decrease in heart attacks.41 Other studies like ATBC showed an increase in strokes. When Vivekananthan and colleagues combined data from several previously published studies, no heart-protective effects of vitamin E were shown. | Dr. Steven R. Gundry See book keywords and concepts | For example, without it beta-carotene can actually act as a dangerous pro-oxidant instead of a beneficial antioxidant. Animals that can manufacture vitamin C, which humans cannot, produce much more of it during times of stress and infection. When you are stressed, going from one time zone to another, undergoing an operation, experiencing a viral or bacterial infection, or just arguing with your spouse, dramatically increase your intake of vitamin C to bowel tolerance, which usually occurs at 6,000 to 10,000 mg per day. | J. Douglas Bremner See book keywords and concepts | When Bjelakovic and colleagues looked at data from several published studies in which vitamin E was given with beta-carotene, there was a 10% overall increase in mortality that nobody can explain. Based on these studies, there is no role for vitamins in the treatment or prevention of heart disease.
HRT AND HEART DISEASE
Since heart disease increases in women after menopause, researchers have long theorized that estrogen and progesterone (which decline after menopause) protect women from heart disease. | | In fact, if anything, there was a tendency to increase mortality, although only about 2%, which is less than that for vitamin A and beta-carotene.
One study of vitamin E combined with vitamin C showed that vitamins actually accelerated the progression of thickening of the coronary arteries and doubled the risk of dying of heart disease. | | In fact, women who might get pregnant should not take multivitamins that have any vitamin A or beta-carotene in them even at lower doses, given their known association with birth defects. The average woman already gets 120% of required vitamin A from diet alone, so there is no need for supplementation. For men who eat a balanced diet that includes fruits and vegetables, there is no need for vitamin A supplementation.
Based on these studies, doctors such as Dr. | | Combining results from several studies showed that patients getting a combination of vitamin A and beta-carotene had a 29% increase in mortality.7 These findings were very surprising to those who conducted the studies, as they were expecting the opposite.
So does that mean we should stop eating carrots? No. Don't forget that vitamin A is essential for survival. However, vitamin A is stored in the liver for long periods of time, and the amount that we get in our diet is more than adequate. | Leslie Taylor, ND See book keywords and concepts | In addition to the chemicals mentioned above, camu-camu contains beta-carotene, calcium, leucine, protein, serine, thiamin, and valine.
There has been no research conducted or published on any medicinal or therapeutic properties of camu-camu. However, there are a few herbal supplement companies in the United States marketing camu-camu extracts in powders and pills and alluding to claims of its benefits—from curing viral infections, colds, flu, cold sores, and autoimmune disorders to even weight loss. The fact is there just isn't any research to back up these claims. | Ray Strand, M.D. See book keywords and concepts | CAROTENOIDS
It is important to have a mixture of carotenoids rather than taking only beta-carotene.
• Beta-carotene—10,000 to 15,000 IU
• Lycopene—1 to 3 mg
• Lutein/Zeaxanthin—1 to 6 mg
• Alpha carotene—500 to 800 meg
VITAMIN C
A mixture of vitamin C is important, especially calcium, potassium, zinc, and magnesium ascorbates, which are much more potent in handling oxidative stress. • 1000 to 2000 mg
Table I, continued
VITAMIN E
It is important to be getting a mixture of natural vitamin Es: d-alpha tocopherol, d-gamma tocopherol, and mixed tocotrienol. | Jonathan V. Wright, M.D. and Alan R. Gaby, M.D. See book keywords and concepts | Antioxidant nutrients: Vitamin A, beta-carotene, vitamin C, vitamin E, and selenium (dosages as recommended by a nutritionally oriented doctor).
• High-potency multiple vitamin and mineral (adjust doses of other nutrients as needed).
Migraine Headache more than 20% of Americans experience migraine headaches at some time during their lives, with women being affected more of en than men. Migraines are sometimes described as "sick headaches. " They can cause intense and throbbing pain and are often associated with nausea, vomiting, diarrhea, visual changes (auras), and sensitivity to light. | | Is that because the thyroid helps convert beta-carotene into vitamin A, and vitamin A can stop heavy menstrual bleeding?"
"Quite possibly. You're catching on already."
"I've heard that a lot of vitamin A can be dangerous."
"With both an abnormal Pap smear and heavy menstrual bleeding, you need a lot for several months. Early warning signs of vitamin A overdose include fatigue, headache, joint pain, muscle aches, bone pain, and hair loss. These side effects disappear if the vitamin is discontinued. | | I'm saying that if you'd been eating enough foods with vitamin A and beta-carotene, you might have prevented those problems in the first place."
"Maybe Jan's onto something with that organic liver, carrot juice, and spinach. But it can't be that simple, can it?"
"Certainly a lot simpler than a D & C operation or freezing your cervix, no? Jan's onto more than just vitamin A. Liver, broccoli, spinach, and many other green leafy vegetables—and fresh-squeezed orange juice, too—are excellent sources of folic acid, also called folate. | | Is beta-carotene OK?" Anna asked.
"Won't hurt, but actual vitamin A is better."
"I have one question, too," Anna said. "I've read that too much vitamin C might cause oxalate kidney stones. Is this true?"
"Theoretically, it's possible. In actuality, I've only observed the possibility twice in 10 years. If it were important for Dmitri to take more than a gram or 2 a day of vitamin C, we could do a urine test to check for oxalate both before and after starting the vitamin C, to see if it might be a problem. | | Also, make sure there's vitamin A, not just beta-carotene, in Jason's multiple vitamin."
"Any special amounts?"
"For now, 15,000 to 25,000 IU of vitamin A. Years ago, a few dermatologists found that hundreds of thousands of units of vitamin A worked against acne . . . but that's a lot, and now there are better alternatives, anyway." "And those are . . . ?"
"In addition to zinc—and in some cases, selenium—there are two very useful natural skin creams. First, 4% niacinamide cream. | | Next, make sure your vitamin A intake is approximately 40,000 IU daily—that's vitamin A itself, not beta-carotene. We'll reduce the dose of vitamin A as you improve. However, while you are taking this amount of vitamin A, it's important that you do not become pregnant, as there is some evidence that taking more than 10,000 IU of vitamin A per day can increase the risk of certain birth defects."
"Oh, you don't have to worry about that."
"Also, zinc—the citrate or picolinate form is best—50 to 60 milligrams daily. Make sure to 'offset' the zinc with 2 to 3 milligrams of copper daily. | Abram Hoffer, PhD, MD, FRCP(C) and Dr. Jonathan Prousjy, DPHE, DSC, ND, FRSH See book keywords and concepts | Of all the organs, the corpus luteum (part of the ovarian follicle) has the highest concentration of beta-carotene. The carotene cleavage activity changes with each ovulation cycle, the highest activity occurring during the mid-ovulation stage. The proper ratio of carotene-to-retinol must be maintained to ensure proper corpus luteum function. Since the corpus luteum produces progesterone, inadequate corpus luteum function could have significant negative clinical effects on the health of the female reproductive system. |
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