Gary Null
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 He began by feeding the vitamin b3 to his son in jam sandwiches because the psychiatric department would not let him give the boy the vitamin. He would go to the hospital every day to take his son out for a walk, and while they were walking he would feed him jam sandwiches with B3. After 6 weeks, the boy said, 'Daddy, I want to go home.' His father took him home. This boy remained well and finished in the fifth percentile in his twelfth-grade exams. After he had been on the vitamin for 18 months, in consultation with me, the father took him off to see if he still needed it. |
| For the patients I work with, I give 3,000 mg per day of either nicotinic acid or nicotinamide, which are both forms of vitamin b3.1 also use vitamin C at the same dose level and sometimes a lot more because vitamin C is a very good water-soluble antioxidant. It is considered the foremost, the most active water-soluble antioxidant present in the human body. That's extremely important.
"In many cases," Dr. Hoffer continues, "we use vitamin B6 as well for a particular group of schizophrenic patients. |
| Abram Hoffer and Humphrey Osmond, pioneers in the field, conducted a double-blind study on the effects of megadoses of vitamin b3 (in the form of niacin or niacinamide) on schizophrenic patients. This was the first such double-blind study performed in the field of psychiatry.
They found that schizophrenia is not purely a behavioral or mental disorder but that it also has a basis in biochemical imbalance, particularly a deficiency of niacin. Schizophrenia is among the most difficult psychiatric conditions to treat. |
| Zinc and the B vitamins, especially thiamine and vitamin Bb are also beneficial. vitamin b3, or niacin, has also been identified as an antistress factor. It lowers cholesterol and triglyceride levels, which are increased by anxiety, and affects the brain in ways that are similar to the effects of tranquilizers. Dr. Lesser is convinced of the efficacy of this nutritional approach, but emphasizes the need to be patient when looking for results. |
| Simply providing the proper vitamin, in this case vitamin b3 or niacin, was the treatment. It cleared up the psychosis.
"There's no doubt that brain function is very dependent upon nutrients like niacin and others, because when they're absent there is apt to be some very disturbed thinking. Depression is one of the symptoms that can occur with this.
"It is important to get all the B-complex vitamins, since they work together. Thiamine, Bb is important, as is riboflavin to a lesser extent. Another important one is B6, pyridoxine. B]2 is still another one that can affect the mental processes. |
Dr. Mary Dan Eades
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 Nutritional value—Choline, essential oils, folic acid, inositol, manganese, pantothenic acid, silicon, vitamin b3. This nutritional herb is a strong antioxidant and useful in the treatment of many disorders.
Medicinal uses—
• Ginger is well known for its anti-inflammatory properties. Indian and Scandinavian studies have consistently shown that this herb is useful for treating most forms of arthritis. The more than 12 antioxidants present in ginger neutralize the free radicals that aid in causing inflammation.
• Thousands of years ago, Chinese sailors chewed gingerroot to combat seasickness. |
Velma J. Keith and Monteen Gordon
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| B Complex, Niacin (See vitamin b3), Vitamin C and E.
—Exercise
—Clean colon.
COLDS—See beginning of this chapter.
COLIC—See Baby Chapter
COLITIS—See Ulcers
CONSTIPATION
Herbal Combinations:
Lower Bowel Combinations
Single Herbs:
Alfalfa Burdock Cascara Sagrada Chickweed
Ginger
Goldenseal Licorice Root
Raspberry
Mandrake Psyllium
Slippery Elm Turkey Rhubarb Yellow Dock
Vitamins & Minerals: Natural Multiple Vit. & Min. Supplement, B Complex
Diet: Real Food Diet, Juice Fasts, Mild Food Diet, Chlorophyll or Green Drinks, Aloe Vera Juice. |
Dr. Mary Dan Eades
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| One such system involves turning dietary tryptophan (an important amino acid or protein building block) into niacin (see Niacin, vitamin b3).
In medical research on female rats found to have low blood levels of vitamin B6 because of deficient intake during pregnancy, doses of as much as 70 times the RDA have failed to restore the levels to normal. This finding could be interpreted in two very different ways: the deficiency was not real (i.e. |
Nicola Reavley
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 In the USA the following are officially listed as vitamins: vitamin A; vitamin C; vitamin D; vitamin E; vitamin K; and the B vitamin complex containing: vitamin B1 (thiamin), vitamin B2 (riboflavin), vitamin b3 (niacin), vitamin B6 (pyridoxine), folic acid, vitamin B12 (cobalamin), biotin and pantothenic acid.
There are other substances whose vitamin status has not been established. Some researchers consider these to be vitamins but this is not generally accepted. Such substances include choline, inositol, para-arninobenzoic acid (PABA) and coenzyme Q10. |
| Niacin, which is also known as vitamin b3, is the common name for both nicotinic acid and nicotinamide (or niacinamide). The niacin deficiency disease, pellagra, was first recognized in the early 18th century but it was not until the 1930s that niacin was found to cure the disease. Niacin is a water soluble white powder and is more resistant to destruction than other B complex vitamins. The body can convert the amino acid tryptophan into niacin. |
Gary Null
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 Some studies indicate that a chromium deficiency, along with a deficiency in its GTF-partner, vitamin b3, may be directly related to several types of schizophrenia.
• Adrenal glands. Chromium is also found in a relatively large amount in your adrenal glands, which with the brain's pituitary gland help you cope with stress.9 Chromium is also an activator of vitamin C, another important element in the proper functioning of these glands.
Who Needs Chromium? |
| Half of the patients were given large daily doses of vitamin b3 along with a supplement containing the other B vitamins plus additional vitamins and minerals. The other patients received placebos.
Here's what Watson and Currier found: on the placebo, seven patients improved, six got worse, and seventeen showed no change. Among the patients taking the vitamins, twenty-two patients showed substantial improvement, two became worse, and six remained the same. With the passing weeks and months of continuing supplementation, the success rate climbed even higher. |
| Nicotinic acid, which you may know as vitamin b3 or niacin, can reduce cholesterol and triglyceride levels in the blood. Side effects are also a danger with frequently prescribed VLDL blood-fat-inhibiting medications such as clofibrate. At a meeting of the Federation of American Societies for Experimental Biology, Dr. Nina Mercer of the University of Western Ontario reported that in a study where soy protein drink was substituted for milk, cholesterol levels were lowered. |
| Several types of schizophrenia may be attributable in part to chromium and vitamin b3 deficiencies.22 Perhaps in the future our mental hospitals will be treating patients with brewer's yeast instead of chemicals and electroshock therapy!
CHROMIUM AND TOXIC METAL POISONING, ARTHRITIS, AND
CANCER
Chromium can also help protect your body from the toxicity of pollution or heavy metal poisoning, because it activates that pollution-protector, vitamin C. It also helps keep your immune system strong when you are exposed to pollution, maintaining your resistance to infections and bacteria. |
Ralph W. Moss, Ph.D.
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 In 1990, Pauling teamed up with Abram Hoffer, MD, PhD, a well-known Canadian biochemist and psychiatrist, who had been treating schizophrenic patients with megadoses of vitamin b3 for decades. Together, they published a study of women with cancer who received high dose vitamin C (17).
The paper used a statistical analysis developed by Pauling in 1989 based on the "Hardin Jones principle" (10,18). This principle was formulated by the late Prof. Hardin Jones of the UC Berkeley in 1956 (19). |
John Boik
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 They include methionine, choline, folic acid, and vitamin B12. of vitamin b3, is synthesized in the body from the amino acid tryptophan. As discussed in Chapter 3, nicotinamide may stimulate angiogenesis.
12.5 SUMMARY
The amount and type of dietary fat consumed may affect cancer growth through numerous mechanisms. High-fat diets, in particular those rich in omega-6 fatty acids, may promote cancer growth. |
| Nicotinamide (niacinamide) is a form of niacin (nicotinic acid, or vitamin b3). The body synthesizes it from the amino acid tryptophan, and it is also available as a vitamin supplement. The effects of nicotinamide supplementation on angiogenesis in humans has yet to be demonstrated. Nicotinamide also decreases blood flow resistance in tumors, and subsequently, lowers the intratumor vascular pressure (Lee et al, 1992). The method by which nicotinamide produces this effect is not understood. |
Gary Null
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| Adult males need a minimum of 18 mg of vitamin b3 daily, and adult females need 13 mg daily. Studies have shown that excessive amounts of B3 can cause glycogen (a starch that helps the body utilize the energy of sugars like glucose) to be consumed hyperactively by the muscles, resulting in the early onset of fatigue. Again, a low-potency vitamin is a worthwhile investment to be sure you are getting sufficient amounts of niacin.
VITAMIN B5 (PANTOTHENIC ACID) Vitamin B5 also works in all our cells. |
Sheldon Saul Hendler and David Rorvik
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 It is sometimes referred to as vitamin b3. Nicotinic acid was first discovered as an oxidation product of nicotine and thus, the origin of its name. In fact, much of the confusion caused by the use of the term niacin for both nicotinic acid and nicotinamide, as well as for nicotinic acid alone, was created by the attempt to dissociate nicotinic acid from its nicotine origins. |
Thomas Bartram
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 Daily. vitamin b3 (lOOmg); Vitamin C (500mg); Calcium pantothenate (500mg). Kelp. Magnesium for mild pain relief and to increase levels of red blood magnesium. Zinc.
POLYNEURITIS. Inflammation of a group of nerves. See: NEURITIS.
POLYP. A small benign growth with a stalk on a mucous membrane. May appear anywhere on the body, usually in the nose, ear, womb or rectum. Commonest site is the nose. Treatment. Numerous cases are recorded of successful use of Garlic internally, and by inserting powder, oil, or sliver of fresh corm into the nostril or meatus of the ear, whichever is affected. |
Textbook of Natural Medicine 2nd Edition Volume 1Michael T. Murray, ND
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| These side-effects have, however, have not been observed in humans supplementing with the esterified form of vitamin b3 (inositol hexaniacinate).
Vitamin B6 (pyridoxine, pyridoxal, pyridoxal 3 phosphate, pyridoxamine, and corresponding phosphorylated forms) (see Table 108.13)
Vitamin B6 is a group of nitrogen-containing compounds
Table 108.13
Pyridoxine (mg)
Category
Age
RDA
Optimal
Males
11-14
1.7
2.0
15-18
2.0
5.0
19-24
2.0
10.0
25-50
2.0
10.0
51 +
2.0
25.0
Females
11-14
1.4
2.0
15-18
1.5
5.0
19-24
1.6
10.0
25-50
1.6
10.0
51 +
1.6
20. |
Gary Null, Ph.D.
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 Vitamin E, another useful antioxidant, should be supplemented in quantities of 400 to 800 IU per day, while 100 mg of vitamin B complex should be consumed three times daily. vitamin b3, also known as niacinamide, is useful in amending blood sugar abnormalities, while B6 tends to shelter the thymus gland from free radical damage.
Zinc picolinate can substantially augment the body's supply of zinc when it's taken in quantities of 35 to 50 mg daily. The picolinate element of the supplement aids in transporting this vital element into the cell. |
| Clinical studies have indicated that niacin, also known as vitamin b3, can help prevent heart attack and heart disease fatality. In addition, evidence suggests that it can be an effective combatant of cancer. Note, though, that niacin should only be taken under medical supervision because of its tendency to hamper liver function.
•Selenium...A lack of this important trace mineral has been associated with hypertension. Generally, 200 meg daily is recommended.
•Taurine... |
Linda B. White, M.D.
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 Your best bet
The Vitamin That's a Drug
Since the 1950s, doctors have prescribed niacin, or vitamin b3, for lowering cholesterol. But the dosages recommended —500 to 3,000 milligrams per day —make this use of the vitamin more like a drug. Niacin lowers not only total cholesterol but also LDL, triglycerides, and fibrinogen, a blood protein responsible for clot formation. It also raises HDL levels. Pure, crystalline niacin can cause a harmless but unpleasant flushing reaction. Taking an aspirin tablet before taking niacin, or using timed-release niacin, can prevent flushing. |
Elson M. Haas, M.D.
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 In a sense tryptophan is really an essential vitamin since it is the precursor of vitamin b3 (niacin); a deficiency of tryptophan, combined with inadequate dietary niacin, can cause the symptoms of pellagra: dermatitis, diarrhea, dementia, and death (the four D's; see the section on Niacin in Chapter 5, Vitamins). Low tryptophan levels are found in many patients with dementia and may have subclinical or subde psychological effects.
Tryptophan has been used effectively to treat insomnia in many people. Serotonin is needed in the brain to induce and maintain sleep. |
James F. Balch, M.D.
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 Again, exercise, garlic, Omega 3 oils, and vitamin b3 (niacin) can eliminate this risk factor.
The third irregularity of the blood is elevated homocysteine.
Homocysteine is an amino acid in the process of changing from methionine to cysteine (one amino acid to another). Normally, it makes the conversion to cysteine and blood levels remain stable, but if it gets stuck in this transitional phase, homocysteine begins to accumulate in the blood. |
| Supplementing the diabetic's diet with vitamin b3 has been shown to have many positive benefits (but take no more than 100 mg daily).
Vitamins B6 B15 and B12
Vitamin B6 (50 to 100 mg daily) supplementation also has significant protective effects against developing diabetic nerve disease, or neuropathy. Vitamin Bp supplementation has been used with success in the diabetic neuropathy patient. Though 1,000 to 3,000 micrograms per day of vitamin B12 by mouth is considered sufficient, injections of vitamin B12 may be necessary, also. |
Elson M. Haas, M.D.
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| Another important fact about vitamin b3 is that it can be manufactured from the amino acid tryptophan, which is essential (needed in the diet). So niacin is not truly essential in the diet when enough protein, containing adequate tryptophan, and other nutrients are consumed. When niacin is not present in sufficient amounts, extra protein is needed. Also, when we are deficient in such nutrients as vitamins B^ B2, and B6, vitamin C, and iron, we cannot easily convert tryptophan to niacin. |
| The best sources of vitamin b3 are liver and other organ meats, poultry, fish, and peanuts, all of which have both niacin and tryptophan. Yeast, dried beans and peas, wheat germ, whole grains, avocados, dates, figs, and prunes are pretty good sources of niacin. Milk and eggs are good because of their levels of tryptophan. Though B3 is stable, the milling and processing of whole grains can remove up to 90 percent of the niacin. Thus, manufacturers will often "enrich" their products by adding niacin. |
| The American Indians, who used corn as the staple in their diet, were able to prevent pellagra, the vitamin b3 deficiency disease, by pounding, soaking, and boiling the corn into a mineral ash (see Niacin discussion in Chapter 5). This sweet yellow grain, however, can provide a lot of nourishment, especially when combined properly with other foods.
Millet. Previously used here mainly as fodder and as birdfeed, millet, also known as sorghum, has recentiy become a more commonly eaten grain, though its food use goes back many thousands of years in China. |
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